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2013年版WHO软组织肿瘤组织学分类

2013年版WHO软组织肿瘤组织学分类

脂肪细胞肿瘤 (adipocytic tumors)

良性 (benign)                                    

脂肪瘤 (lipoma) 

脂肪瘤病 (lipomatosis) 

神经脂肪瘤病 (lipomatosis of nerve)  

脂肪母细胞瘤/脂肪母细胞瘤病 (lipoblastoma/ lipoblastomasis) 

血管脂肪瘤 (angiolipoma)

肌脂肪瘤 (myolipoma)

软骨样脂肪瘤 (chondroid lipoma)

肾外血管平滑肌脂肪瘤 (extra-renal angiomyolipoma)

肾外髓脂肪瘤  (extra-andrenal myelipoma)

梭形细胞/多形性脂肪瘤 (spindle cell/ pleomorphic lipoma)

冬眠瘤 (hibernoma)


中间型(局部侵袭性) ( intermediate type, locally aggressive)

非典型脂肪瘤性肿瘤/ (atypical lipomatous tumor/well differentiated liposarcoma)          

高分化脂肪肉瘤                    

恶性 (malignant)

去分化脂肪肉瘤 (dedifferentiated liposarcoma)       

黏液样脂肪肉瘤 (mucinous liposarcoma)         

多形性脂肪肉瘤 (pleomorphic liposarcoma)     

脂肪肉瘤,非特殊类型  (liposarcoma, not otherwise specified)


纤维母细胞性/肌纤维母细胞性肿瘤 (fibroblastic/ myofibroblastic tumors)

良性 (benign)

结节性筋膜炎 (nodular fasciitis)   

增生性筋膜炎 (proliferative fasciitis)

增生性肌炎 (proliferative myositis)

骨化性肌炎 (myositis ossificans) 

指趾纤维-骨性假瘤( fibrous-osseous pseudotumor of digits)

缺血性筋膜炎 (ischemic fasciitis)

弹力纤维瘤  (elastofibroma)     

婴儿纤维错构瘤  (fibrous harmatoma of infancy)           

颈部纤维瘤病  (fibromatosis colli)

幼年性透明变性纤维瘤病 (juvenile hyaline fibromatosis)

包涵体性纤维瘤病 (inclusion body fibromatosis)

腱鞘纤维瘤  (fibroma of tendon sheath) 

促纤维结缔组织增生性纤维母细胞瘤 (desmoplastic fibroblastoma)

乳腺型肌纤维母细胞瘤 (mammary type myofibroblastoma)

钙化性腱膜纤维瘤 (calcifying aponeurotic fibroma) 

血管肌纤维母细胞瘤 (angiomyofibroblastoma)

富于细胞性血管纤维瘤 (cellular angiofibroma) 

项型纤维瘤 (Nuchal-type fibroma ) 

Gardner纤维瘤 (Gardner fibroma)

钙化性纤维性肿瘤 (calcifying fibrous tumor)


中间型(局部侵袭性) (intermediated, locally aggressive)

/跖纤维瘤病 (palmar/plantar fibromatosis)

韧带样纤维瘤病 (desmoid-type fibromatosis)

脂肪纤维瘤病 (lipofibromatosis)

巨细胞纤维母细胞瘤 (giant cell fibroblastoma)


中间型(罕见转移性) (intermediated, rarely metastasizing)

隆突性皮纤维肉瘤  (dermatofibrosarcoma protuberans)

纤维肉瘤性隆突性皮纤维肉瘤 (fibrosarcomatou dermatofibrosarcoma protuberans)

色素性隆突性皮纤维肉瘤 (pigmented dermatofibroarcoma protuberans)

孤立性纤维肿瘤(solitary fibrous tumor)

孤立性纤维肿瘤恶性 (solitary fibrous tumor, malignant)

炎症性肌纤维母细胞肿瘤 (inflammatory myofibroblastic tumor)

低级别肌纤维母细胞肉瘤 (low-grade myofibroblastoma)

黏液炎性纤维母细胞肉瘤  (myxoinflammatory fibroblastic sarcoma )

非典型黏液炎性纤维母细胞肿瘤 (atypical myxoinflammatory fibroblastic tumor)

婴儿纤维肉瘤 (infantile fibrosarcoma)


恶性 (malignant)

成年纤维肉瘤 (adult fibrosarcoma)

黏液性纤维肉瘤 (myxoid fibrosarcoma)

低级别纤维黏液样肉瘤 (low-grade fibromyxoid sarcoma)

硬化性上皮样纤维肉瘤 (sclerosing epithelioid fibrosarcoma)


所谓纤维组织细胞性肿瘤 (so-called fibrohistiocytic tumors)

良性 (benign)

腱鞘巨细胞肿瘤 (tenosynovial giant cell tumor )   

局限型 (localized type)  

弥漫型 ( diffuse type)     

恶性 (malignant)

深部良性纤维组织细胞瘤 (deep benign fibrous histiocytoma)


中间型(罕见转移性) (intermediate, rarely metastasizing)

丛状纤维组织细胞性肿瘤 (plexiform fibrohistiocytoma)

软组织巨细胞肿瘤 (giant cell tumor of soft tissue) 


平滑肌肿瘤 (smooth muscle tumors)

良性 (benign) 

深部平滑肌瘤  (deep leiomyoma)

恶性 (malignant)

平滑肌肉瘤(皮肤除外)  (leiomyosarcoma, excluding skin)


周细胞(血管周肿瘤 (pericytic (perivascular) tumors)

球瘤(和变异型)  (glomus tumor, variants)

球血管瘤病  (glomangiomatosis)

恶性球瘤  (malignant glomus tumor)

肌周细胞瘤 (myopericytoma)

肌纤维瘤  (myofibroma)

肌纤维瘤病 (myofibromatosis)

血管平滑肌瘤  (angioleiomyoma)


骨骼肌肿瘤 (skeletal muscle tumor)

良性 (benign)

横纹肌瘤 (rhabdomyoma)

成人型 (Adult type) 

胚胎型 (fetal type)  

生殖道型 (genital type)


恶性 (malignant)

胚胎性横纹肌肉瘤(包括葡萄簇、间变性) (embryonal rhabdomyosarcoma, including botryoid and anaplastic )

腺泡状横纹肌肉瘤(包括实性、间变性)(alveolar rhabdomyoarcoma, including solid and anaplastic )

多形性横纹肌肉瘤  (pleomorphic rhabdomyosarcoma)

梭形细胞/硬化性横纹肌肉瘤 (spindle cell/ sclerosing rhabdosarcoma)


软组织血管肿瘤 (vascular tumors of soft tissue)

良性 (benign)

血管瘤  (haemangioma)

滑膜 (synovial) 

静脉  (vein)  

动静脉血管瘤/血管畸形 (arterioveinous haemangioma/ malformation )

肌内 (intramuscular)

上皮样血管瘤 (epithelioid haemangioma)

血管瘤病   (angiomatosis)   

淋巴管瘤   (lymphangioma)


中间型(局部侵袭性)(intermediate, locally aggressive)

卡波氏样血管内皮细胞瘤   (kaposiform haemangioendothelioma )


中间型(罕见转移性)(intermediate, rarely metastasizing )

网状血管内皮细胞瘤    (retiform haemangioendothelioma) 

乳头状淋巴管内内皮细胞瘤 (papillary intralymphatic angioendothelioma)

组合型血管内皮细胞瘤 (composite haemangioendothelioma)     9136/1

假肌性(上皮样肉瘤样)血管内皮细胞瘤 (pseudomyogenic (epithelioid sarcoma-like) haemangioendothelioma)  

卡波氏肉瘤 (kaposisarcoma)    


恶性 (malignant)

上皮样血管内皮细胞瘤 (epithelioid haemangiendothelioma) 

软组织血管肉瘤 (angiosarcoma of soft tissue)       


软骨-骨组织肿瘤 (chondro-osseous tumors)

软组织软骨瘤 (soft tissue chondroma )     

骨外间叶性软骨肉瘤 (extraskeletal mesenchymal chondrosarcoma )

骨外骨肉瘤 (extraskeletal osteosarcoma )         


胃肠道间质肿瘤  (gastrointestinal stromal tumors)

良性,胃肠道间质肿瘤 (benign gastrointestinal stromal tumor)  

胃肠道间质肿瘤,恶性潜能未定 (gastrointestinal stromal tumor, uncertain malignant potential )胃肠道间质肿瘤,恶性(gastrointestinal stromal tumor, malignant)   


神经鞘肿瘤 (nerve sheath tumors)

良性 (benign)

神经鞘瘤(包括变异型)(Schwannoma, including variants )  

色素性神经鞘瘤  (pigmented Schwannoma)     

经纤维瘤 (包括变异型)(neurofibroma, including variants )

丛状神经纤维瘤 (plexiform neurofibroma)     

神经束膜瘤     (perineurioma)        

恶性神经束膜瘤(malignant neurioma)      

颗粒细胞瘤  (granular cell tumor)            

皮肤神经鞘黏液瘤 (dermal nerve sheath myxoma)       

孤立性局限性神经瘤 (solitary circumscribed neuroma)      

异位性脑膜瘤  (ectopic meningioma)         

鼻腔神经胶质异位 (nasal glial heterotopia )     

良性“蝾螈”肿瘤 (bengin Triton tumor)

杂合性神经鞘肿瘤 (hybrid nerve sheath tumors)    


恶性 (malignnat)

恶性周围神经鞘肿瘤 (malignant peripheral nerve sheath tumor)          

上皮样恶性周围神经鞘肿瘤 (epithelioid malignant peripheral nerve sheath tumor)    

恶性“蝾螈”肿瘤  (malignant Triton tumor)           

恶性颗粒细胞肿瘤 (malignant granular cell tumor)           

外胚层间叶瘤 (ectomesenchymaoma)            


分化未定肿瘤 (tumor of uncertain differentiation)

良性 (benign)

指端纤维黏液瘤  (acral fibromyxoma)           

肌内黏液瘤(包括富于细胞变异型)(intramuscular myxoma, including cellular variants  ) 

关节旁黏液瘤 (juxta-articular myxoma)               

深部“侵袭性”血管黏液瘤 (deep aggressiveangiomyxoma)  

多形性透明变性血管扩张性肿瘤(pleomorphic hyalinizing angioectatic tumor) 

异位性错构瘤性胸腺瘤 (ectopic harmartomatous thymoma)      

中间型(局部侵袭性)(intermediate, locally aggressive)

含铁血黄素性纤维脂肪性肿瘤 (haemosiderotic fibrolipomatous tumor)

中间型(罕见转移性)(intermediate, rarely metastasizing)

非典型性纤维黄色瘤 (atypical fibroxanthoma)       

血管瘤样纤维组织细胞瘤 (angiomatoid fibrous histiocytoma)    

骨化性纤维黏液样肿瘤 (ossifying fibromyxoid tumor)      

骨化性纤维黏液样肿瘤,恶性(ossifying fibromyxoid tumor, malignant)   

混合性肿瘤,非特殊类型 (mixed tumor, NOS)    

混合型肿瘤,非特殊类型,恶性 (mixed tumor, NOS, malignant)  

肌上皮瘤 ( myoepithelioma)                 

肌上皮癌   (myoepithelial carcinoma)                 

磷酸盐尿性间叶性肿瘤,良性 (phosphaturic mesenchymal tumor, benign)   

磷酸盐尿性间叶性肿瘤,恶性  (phosphaturic mesenchymal tumor,malignnat)  

恶性 (malignnat)

滑膜肉瘤,非特殊类型 (synovial sarcoma, NOS)       

滑膜肉瘤,梭形细胞型 (synovial sarcoma, spindle cell )    

滑膜肉瘤,双相型 (synovial sarcoma, biphasic)       

上皮样肉瘤  (epithelioid sarcoma)                

腺泡状软组织肉瘤  (alveolar soft part sarcoma)          

软组织透明细胞肉瘤  (clear cell sarcoma of soft tissue)        

骨外黏液性软骨肉瘤  (extraskeletal myxoid chondrosarcoma)        

骨外尤文氏肉瘤    (extraskelatal Ewing sarcoma)          

促纤维结缔组织增生性小圆形细胞肿瘤 (desmoplastic small round cell tumor)   

肾外横纹肌样肿瘤 (extrarenal rhabdoid tumor)         

血管周上皮样细胞分化肿瘤(PEComa(neoplasms with perivascular epithelioid cell differentiation, PEComa)

PEComa, 非特殊类型 良性 (PEComa, NOS,  benign)      

PEComa, 非特殊类型 恶性 ( PEComa,NOS, malignant)      

内膜肉瘤   (intimal sarcoma)               


未分化/未能分类肉瘤(undifferentiated/unclassified sarcoma 

未分化梭形细胞肉瘤 (undifferentiated spindle cell sarcoma)     

未分化多形性肉瘤 (undifferentiated pleomorphic sarcoma)     

未分化圆形细胞肉瘤 (undifferentiated round cell sarcoma)     

未分化上皮样肉瘤 (undifferentiated epithelioid sarcoma)     

未分化肉瘤,非特殊类型 (undifferentiated sarcoma, NOS)   


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