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2020年版WHO食管肿瘤组织学分类

a.    Benign epithelial tumors/precursors良性上皮肿瘤/前驱病变

                                          i.    Squamous cell papilloma

鳞状细胞乳头状瘤

                                         ii.    Esophageal squamous intraepithelial neoplasia (dysplasia), low-grade

食管鳞状上皮内瘤变(异型增生),低级别

                                        iii.    Esophageal squamous intraepithelial neoplasia (dysplasia), high-grade

食管鳞状上皮内瘤变(异型增生),高级别

                                       iv.    Esophageal glandular dysplasia (intraepithelial neoplasia), low-grade

食管腺异型增生(上皮内瘤变),低级别

                                        v.    Esophageal glandular dysplasia (intraepithelial neoplasia), high-grade

食管腺异型增生(上皮内瘤变),高级别

b.    Malignant epithelial tumors恶性上皮肿瘤

                                          i.    Adenocarcinoma

腺癌

                                         ii.    Adenoid cystic carcinoma

腺样囊性癌

                                        iii.    Mucoepidermoid carcinoma

黏液表皮样癌

                                       iv.    Adenosquamous carcinoma

腺鳞癌

                                        v.    Squamous cell carcinoma鳞状细胞癌

1.    Verrucous squamous cell carcinoma

疣状鳞状细胞癌

2.    Spindle cell squamous carcinoma

梭形细胞鳞状细胞癌

3.    Basaloid squamous cell carcinoma

基底样鳞状细胞癌

                                       vi.    Undifferentiated carcinoma

未分化癌

                                      vii.    Lymphoepithelioma like carcinoma

淋巴上皮瘤样癌

                                     viii.    Neuroendocrine tumor神经内分泌肿瘤

1.    Neuroendocrine tumor, grade 1

神经内分泌肿瘤,G1

2.    Neuroendocrine tumor, grade 2

神经内分泌肿瘤,G2

3.    Neuroendocrine tumor, grade 3

神经内分泌肿瘤,G3

                                       ix.    Neuroendocrine carcinoma神经内分泌癌

1.    Large cell neuroendocrine carcinoma

大细胞神经内分泌癌

2.    Small cell neuroendocrine carcinoma

小细胞神经内分泌癌

                                        x.    Mixed neuroendocrine–non–neuroendocrine neoplasm (MiNEN)混合性神经内分泌-非神经内分泌肿瘤

1.    Combined small cell–adenocarcinoma

混合性小细胞癌-腺癌

2.    Combined small cell–squamous cell carcinoma

混合性小细胞癌-鳞状细胞癌



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