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2020年版WHO胃肿瘤组织学分类

a.    Benign epithelial tumors/precursors良性上皮肿瘤/前驱病变

                                          i.    Glandular intraepithelial neoplasia (including intestinal type, foveolar type, gastric pit/crypt, serrated)腺上皮内瘤变(包括肠型、小凹型、胃小凹底部或隐窝型、锯齿状型)

1.    Stomach glandular intraepithelial neoplasia,Low-grade

胃腺上皮内瘤变,低级别

2.    Stomach glandular intraepithelial neoplasia,High-grade

胃腺上皮内瘤变,高级别

                                         ii.    Intestinal type adenoma/adenomatous polyp肠型腺瘤/腺瘤性息肉

1.    Intestinal type adenoma/adenomatous polyp,Low-grade

肠型腺瘤/腺瘤性息肉,低级别

2.    Intestinal type adenoma/adenomatous polyp,High-grade

肠型腺瘤/腺瘤性息肉,高级别

b.    Malignant epithelial tumors恶性上皮肿瘤

                                          i.    Adenocarcinoma腺癌

1.    Tubular adenocarcinoma

管状腺癌

2.    Parietal cell carcinoma

壁细胞癌

3.    Adenocarcinoma with mixed subtypes

混合型腺癌

4.    Papillary adenocarcinoma

乳头状腺癌

5.    Micropapillary adenocarcinoma

微乳头状腺癌

6.    Mucoepidermoid carcinoma

黏液表皮样癌

7.    Mucinous adenocarcinoma

黏液腺癌

8.    Signet ring cell carcinoma

印戒细胞癌

9.    Poorly cohesive carcinoma

低黏附性癌

10.  Medullary carcinoma with lymphoid stroma

髓样癌伴有淋巴样间质

11.  Hepatoid adenocarcinoma

肝样腺癌

12.  Paneth cell carcinoma

潘氏细胞癌

                                         ii.    Squamous cell carcinoma

鳞状细胞癌

                                        iii.    Adenosquamous cell carcinoma

腺鳞癌

                                       iv.    Undifferentiated carcinoma未分化癌

1.    Large cell carcinoma with rhabdoid phenotype

具有横纹肌样表型的大细胞癌

2.    Pleomorphic carcinoma

多形性癌

3.    Sarcomatoid carcinoma

肉瘤样癌

4.    Carcinoma with osteoclast-like giant cell

伴有破骨样巨细胞的癌

                                        v.    Gastroblastoma

胃母细胞瘤

                                       vi.    Neuroendocrine tumor神经内分泌肿瘤

1.    Neuroendocrine tumor, Grade 1

神经内分泌肿瘤,G1

2.    Neuroendocrine tumor, Grade 2

神经内分泌肿瘤,G2

3.    Neuroendocrine tumor, Grade 3

神经内分泌肿瘤,G3

4.    Gastrinoma

胃泌素瘤

5.    Somatotastinoma

生长抑素瘤

6.    Enterochromaffin cell carcinoid

肠嗜铬细胞类癌

7.    ECL-cell carcinoid, malignant

ECL细胞类癌,恶性


                                      vii.    Neuroendocrine carcinoma神经内分泌癌

1.    Large cell neuroendocrine carcinoma

大细胞神经内分泌癌

2.    Small cell neuroendocrine carcinoma

小细胞神经内分泌癌

                                     viii.    Mixed neuroendocrine–non-–neuroendocrine neoplasm (MiNEN)

混合性神经内分泌-非神经内分泌肿瘤


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