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2019 WHO乳腺上皮源性肿瘤分类

2019 WHO乳腺上皮源性肿瘤分类

 

Benign epithelial proliferations and precursors良性上皮增生和前驱病变

Usual ductal hyperplasia 普通型导管上皮增生

Columnar cell lesions, including flat epithelial atypia柱状细胞病变,包括扁平上皮非典型

Atypical ductal hyperplasia非典型导管增生

Adenosis and benign sclerosing lesions腺病和良性硬化性病变

Sclerosing adenosis硬化性腺病

8401/0   Apocrine adenoma大汗腺腺病

Microglandular adenosis微腺腺病

Radial scar / complex sclerosing lesion放射状瘢痕/复杂性硬化性病变

 

Adenomas腺瘤

8211/0   Tubular adenoma NOS小管腺瘤

8204/0   Lactating adenoma泌乳性腺瘤

8503/0   Duct adenoma NOS导管腺瘤非特指型

 

Epithelial-myoepithelial tumours 上皮肌上皮肿瘤

8940/0   Pleomorphic adenoma多形性腺瘤

8983/0   Adenomyoepithelioma NOS腺肌上皮瘤非特指型

8983/3   Adenomyoepithelioma with carcinoma腺肌上皮瘤伴癌

8562/3   Epithelial-myoepithelial carcinoma上皮肌上皮癌

 

Papillary neoplasms乳头状肿瘤

8503/0   Intraductal papilloma导管内乳头状瘤

8503/2   Ductal carcinoma in situ, papillary乳头状导管原位癌

8504/2   Encapsulated papillary carcinoma包裹性乳头状癌

8504/3   Encapsulated papillary carcinoma with invasion 包裹性乳头状癌伴浸润

8509/2   Solid papillary carcinoma in situ原位实性乳头状癌

8509/3   Solid papillary carcinoma with invasion实性乳头状癌伴浸润

8503/3   Intraductal papillary adenocarcinoma with invasion导管内乳头状腺癌伴浸润

 

Non-invasive lobular neoplasia非浸润性小叶性肿瘤

Atypical lobular hyperplasia 非典型小叶增生

8520/2   Lobular carcinoma in situ NOS小叶原位癌非特指型

Classic lobular carcinoma in situ经典型小叶原位癌

Florid lobular carcinoma in situ旺织性小叶原位癌

8519/2     Lobular carcinoma in situ, pleomorphic.多形性小叶原位癌

 

Ductal carcinoma in situ (DCIS)导管原位癌

8500/2   Intraductal carcinoma, non-infiltrating, NOS导管内癌,非浸润性,非特指

DCIS of low nuclear grade低级别核导管原位癌

DCIS of intermediate nuclear grade中级别核导管原位癌

DCIS of high nuclear grade高级别核导管原位癌

 

 

Invasive breast carcinoma浸润性乳腺癌

8500/3  Infiltrating duct carcinoma NOS 浸润性导管癌非特指型

8290/3  Oncocytic carcinoma嗜酸细胞癌

8314/3  Lipid-rich carcinoma富于脂质癌

8315/3  Glycogen-rich carcinoma 富于糖原癌

8410/3  Sebaceous carcinoma 皮脂腺癌

8520/3  Lobular carcinoma NOS 小叶癌非特指

8211/3  Tubular carcinoma小管癌

8201/3  Cribriform carcinoma NOS筛状癌非特指

8480/3  Mucinous adenocarcinoma黏液性癌

8470/3  Mucinous cystadenocarcinoma NOS黏液性囊性癌非特指

8507/3  Invasive micropapillary carcinoma of breast 浸润性微乳头状癌

8401/3  Apocrine adenocarcinoma大汗腺腺癌

8575/3  Metaplastic carcinoma NOS化生性癌非特指

 

Rare and salivary gland-type tumours少见和涎腺型癌

8550/3  Acinar cell carcinoma腺泡细胞癌

8200/3  Adenoid cystic carcinoma腺样囊性癌

Classic adenoid cystic carcinoma 经典型腺样囊性癌

Solid-basaloid adenoid cystic carcinoma 实性基地样腺样囊性癌

Adenoid cystic carcinoma with high-grade transformation

  腺样囊性癌伴高级别转化

3502/3     Secretory carcinoma分泌性癌

8430/3     Mucoepidermoid carcinoma粘液表皮样癌

8525/3     Polymorphous adenocarcinoma多形态腺癌

8509/3     Tall cell carcinoma with reversed polarity高细胞癌伴极向反转

 

Neuroendocrine neoplasms神经内分泌肿瘤

8240/3   Neuroendocrine tumour NOS神经内分泌肿瘤非特指

8240/3   Neuroendocrine tumour, grade 1 神经内分泌肿瘤1

8249/3   Neuroendocrine tumour, grade 2神经内分泌肿瘤2

8246/3   Neuroendocrine carcinoma NOS神经内分泌癌非特指

8041/3   Neuroendocrine carcinoma, small cell 小细胞神经内分泌癌

8013/3   Neuroendocrine carcinoma, large cell大细胞神经内分泌癌


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