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2021 第五版WHO胸腺及纵隔肿瘤分类


上皮性肿瘤 Epithelial tumours

胸腺瘤(thymomas)

8580/3 胸腺瘤, 非特指型  Thymoma, NOS

8581/3 胸腺瘤,A型  Thymoma, type A

8582/3 AB型胸腺瘤(thymoma,type AB )

8583/3 B1型胸腺瘤(thymoma,type B1 )

8584/3 B2型胸腺瘤(thymoma,type B2 )

8585/3 B3型胸腺瘤( thymoma,type B3)

8580/1 微小结节性胸腺瘤伴淋巴样间质

(micronodular thymoma with lymphoid stroma)

8580/3 化生型胸腺瘤(metaplastic thymoma)

9010/0 脂肪纤维腺瘤(lipofibroadenoma)

胸腺癌(包括胸腺神经内分泌上皮肿瘤)(thymic carcinoma)

鳞状细胞癌(squamous cell carcinoma)

8070/3鳞状细胞癌,非特指 (squamous cell carcinoma, NOS)

8123/3基底细胞样癌(basaloid carcinoma)

8123/3淋巴上皮瘤样癌(lymphoepithelioma-like carcinoma)

腺癌(adenocarcinoma)

8140/3腺癌,非特指型  Adenocarcinoma, NOS

8260/3低级别乳头状腺癌(Low-grade papillary adenocarcinoma)

8200/3胸腺癌伴腺样囊腺癌样特征

thymoma with adenoid cystic carcinoma-like features

8144/3 腺癌,肠型 Adenocarcinoma, enteric type

8560/3腺鳞癌 Adenosquamous carcinoma

NUT癌 (NUT carcinoma)

8023/3 NUT癌 (NUT carcinoma)

涎腺样癌 Salivary gland-like carcinomas

8430/3 黏液表皮样癌 Mucoepidermoid carcinoma

8310/3透明细胞癌 Clear cell carcinoma

8033/3肉瘤样癌Sarcomatoid carcinoma

8980/3 癌肉瘤 Carcinosarcoma

未分化癌 Undifferentiated carcinoma

8020/3癌,未分化,非特指Carcinoma, undifferentiated, NOS

胸腺癌Thymic carcinomas

8586/3胸腺癌,非特指 thymic carcinoma, NOS

胸腺神经内分泌肿瘤 thymic neuroendocrine tumours

8240/3 类癌,非特指/神经内分泌瘤,非特指

Carcinoid tumor, NOS/neuroendocrine tumor, NOS

8240/3典型类癌/神经内分泌瘤,1级

Typical carcinoid/neuroendocrine tumor, grade 1

8249/3不典型类癌/神经内分泌瘤,2级

Typical carcinoid/neuroendocrine tumor, grade 1

神经内分泌癌Neuroendocrine carcinomas

8041/3小细胞癌 small cell carcinoma                                 

8045/3混合性小细胞癌 combined small cell carcinoma

8013/3大细胞神经内分泌癌 large cell neuroendocrine  carcinoma


纵膈生殖细胞肿瘤 Germ cell tumours of the mediastinum

9061/3精原细胞瘤 seminoma

9070/3胚胎性癌embryonal carcinoma

9071/3卵黄囊瘤 York sac tumour

9071/3绒毛膜癌 choriocarcinoma

畸胎瘤 teratoma

9080/0成熟性畸胎瘤 teratoma,mature

9080/1不成熟畸胎瘤 teratoma,immature

9085/3 混合性生殖细胞肿瘤Mixed germ cell tumor

9084/3畸胎瘤伴体细胞型恶性成分 Teratoma with somatic-type malignancy

9086/3生殖细胞肿瘤伴相关恶性血液肿瘤 germ cell tumour with associated haemotologic malignancy

胸腔间叶性肿瘤Mesenchymal Tumors of the Thorax

脂肪肿瘤Adipocytic tumors

8850/0脂肪瘤,非特指 Lipoma, NOS

8850/0胸腺脂肪瘤Thymolipoma

8850/3脂肪肉瘤,非特指 Liposarcoma, NOS

8851/3脂肪肉瘤,高分化Liposarcoma, well differentiated

8852/3黏液样脂肪肉瘤 Myxoid liposarcoma

8852/3多形性脂肪肉瘤pleomorphic liposarcoma

8858/3去分化脂肪肉瘤  dedifferentiated liposarcoma

纤维和纤维母细胞性肿瘤Fibroblastic and myofibroblastic tumors

8858/3韧带样型纤维瘤病Desmoid-type fibromatosis

8815/1孤立性纤维性肿瘤,非特指 solitary fibrous tumourNOS

8817/0钙化性纤维性肿瘤Desmoid-type fibromatosis

8825/1炎性肌纤维母细胞性肿瘤Inflammatory myofibroblastic tumor

8825/1粘液纤维肉瘤Myxofibrosarcoma

脉管肿瘤vascular neoplasms

8825/1血管瘤,非特指 Hemangioma, NOS

8825/1海绵状血管瘤cavernous hemangioma

8825/1静脉血管瘤Venous hemangioma

8825/1肌内血管瘤Intramuscular hemangioma

8825/1动静脉血管瘤Arteriovenous hemangioma

9170/0淋巴管瘤,非特指 lyphangioma,NOS

9173/0囊性淋巴管瘤 Cystic lymphangioma

9133/3上皮样血管内皮细胞瘤

epithelioid hemangioendothelioma

9120/3血管肉瘤andiosarcoma

骨骼肌肿瘤 Skeletal muscle tumors

8900/3横纹肌肉瘤,非特指  Rhabdomyosarcoma, NOS

8910/3胚胎型横纹肌肉瘤 Embryonal rhabdomyosarcoma

8912/3梭形细胞横纹肌肉瘤Spindle cell rhabdomyosarcoma

8912/3腺泡状横纹肌肉瘤Alveolar rhabdomyosarcoma

8901/3多形性横纹肌肉瘤Alveolar rhabdomyosarcoma

外周神经鞘和神经肿瘤Peripheral nerve sheath and neural tumors

8693/3肾上腺外副神经节瘤Extra-adrenal paraganglioma

9580/0颗粒细胞瘤Granular cell tumor

9580/3颗粒细胞瘤,恶性 Granular cell tumormalignant

9580/0神经鞘瘤Schwannoma

9540/3恶性外周神经鞘瘤Malignant peripheral nerve sheath tumor

9490/3节细胞神经瘤ganglioneuroma

9490/3节细胞神经母细胞瘤ganglioneuroblastoma

9500/3神经母细胞瘤neuroblastoma

分化不明肿瘤Tumors of uncertain differentiation

9500/3滑膜肉瘤,非特指 synovial sarcomaNOS

9500/3滑膜肉瘤,梭形细胞synovial sarcoma,spindle cell

9500/3滑膜肉瘤,上皮样细胞synovial sarcoma,epithelioid cell

9043/3滑膜肉瘤,双向型synovial sarcoma,biphasic

9043/3尤文肉瘤 Ewing sarcoma

9367/3 CIC重排肉瘤 CIC-rearranged sarcomaI

9368/3肉瘤伴BCOR基因改变Sarcoma with BCOR genetic alterations

9366/3圆细胞肉瘤伴EWSR1-non-ETS融合

Round cell sarcoma with EWSR1-non-ETS fusions

 

以下淋巴造血肿瘤分类为2015 年第四版分类

纵膈淋巴瘤 lymphoma of the mediastinum 2015 年第四版)


原发性纵隔大B细胞淋巴瘤Primary mediastinal large B-cell lymphoma

黏膜相关淋巴组织结外边缘区淋巴瘤 (MALT淋巴瘤)Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)

其它成熟B细胞淋巴瘤 other ature B-Cell lymphoma

T 淋巴母细胞白血病/淋巴瘤T-ALL/LBL T lymphoblastic leukemia/lymphoma

间变大细胞淋巴瘤和其它少见成熟T和NK细胞淋巴瘤Anaplastic large cell lymphoma and other rare mature T- and NK-Cell lymphomas

ALK阳性间变大细胞淋巴瘤ALCL ,ALK-positive(ALK+)

ALK阴性间变大细胞淋巴瘤ALCL ,ALK-negative(ALK-)

霍奇金淋巴瘤Hodgkin lymphoma

B细胞淋巴瘤,不能分类,特征介于弥漫大B细胞淋巴瘤与经典型霍奇金淋巴瘤之间

B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma


纵膈组织细胞及树状突细胞肿瘤 Histocytic and dendritic cell neoplasms of the mediastinum

朗格罕细胞病变Langerhans cell lesions

朗格罕细胞组织细胞增多症Langerhans cell histiocytosis(LCH)

朗格罕细胞肉瘤Langerhans cell sarcoma(LCS)

组织细胞肉瘤Histiocytic sarcoma

滤泡状树突细胞肉瘤Follicular dendritic cell sarcoma(FDC)

指状突树突细胞肉瘤Interdigitating dendritic cell sarcoma(IDC)

纤维母细胞性网状细胞肿瘤 Fibroblastic reticular cell tumor

未确定的树状突细胞肿瘤Indeterminate dendritic cell tumor

髓系肉瘤和髓外急性髓系白血病Myeloid sarcoma and extramedullary acute myeloid leukemia




胸腺异位肿瘤 ectopic tumours of the thymoma

异位甲状腺肿瘤 ectopic thyroid tumours

异位甲状旁腺肿瘤ectopic parathyroid tumours

其它见异位肿瘤 other rare ectopic tumours



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