1. 早期表现为乳晕下导管为中心的慢性炎症,逐步扩展到周围组织;
2. 导管扩张,腔内可见泡沫样组织细胞、蛋白性分泌物、胆固醇结晶或钙化;
3. 导管周围淋巴细胞、浆细胞、组织细胞浸润,可见异物巨细胞或伴肉芽肿形成;
4. 可伴脓肿,甚至窦道形成;
5. 上皮萎缩,或可鳞状上皮化生;
6. 晚期导管周围纤维化可引起导管阻塞,上皮完全消失。
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