2014年版WHO子宫颈肿瘤组织学分类

上皮性肿瘤(epithelial tumours)

鳞状上皮肿瘤及前期病变(squamous cell tumours and precursors)

鳞状上皮内病变(squamous intraepithelial lesions)

低级别鳞状上皮内病变(low-grade squamous intraepithelial lesion)

高级别鳞状上皮内病变(high-grade squamous intraepithelial lesion)

鳞状细胞癌,非特指型(squamous cell carcinoma, NOS)

角化型 (keratinizing)

非角化型(non-keratinizing)

乳头型(papillary)

基底细胞样(basaloid)

疣状(warty)

湿疣状(verrucous)

鳞状移行细胞癌(squamotransitional)

淋巴上皮瘤样(lymphoepithelioma-like)

良性鳞状上皮病变(benign squamous cell lesions)

鳞状上皮化生(squamous metaplasia)

尖锐湿疣(condyloma acuminatum)

鳞状上皮乳头状瘤(squamous papilloma)

移行上皮化生(transitional metaplasia)

腺体肿瘤及前期病变(glandular tumours and precursors)

原位腺癌(adenocarcinoma in situ)

腺癌(adenocarcinoma)

宫颈腺癌,普通型(endocervical adenocarcinoma, usual type)

黏液性癌,非特指型(mucinous carcinoma,NOS)

胃型(gastric type)

肠型(intestinal type)

印戒细胞型(signet-ring cell type)

绒毛腺样癌(villoglandular carcinoma)

子宫内膜样癌(endometrioid carcinoma)

透明细胞癌(clear cell carcinoma)

浆液性癌(serous carcinoma)

中肾管型癌(mesonephric carcinoma)

伴有神经内分泌癌的腺癌(adenocarcinoma admixed with neuroendocrine carcinoma)

良性腺体肿瘤和瘤样病变(benign glandular tumours and tumour-like lesions)

宫颈息肉(endocervical polyp)

米勒源性乳头状瘤(müllerian papilloma)

子宫颈腺囊肿(Nabothian cyst)

隧道样腺丛(tunnel clusters)

微腺体增生(microglandular hyperplasia)

分叶状宫颈内膜腺体增生(lobular endocervical glandular hyperplasia)

弥漫性层状宫颈内膜腺体增生(diffuse laminar endocervical hyperplasia)

中肾管残件及其增生(mesonephric remnants and hyperplasia)

Arias-Stella反应(Arias-Stella reaction)

宫颈内膜异位(endocervicosis)

宫颈子宫内膜异位(endometriosis)

输卵管子宫内膜样化生(tuboendometrioid metaplasia)

异位前列腺组织(ectopic prostate tissue)

其他上皮性肿瘤(other epithelial tumours)

腺鳞癌(adenosquamous carcinoma)

毛玻璃细胞亚型(glassy cell carcinoma)

腺样囊性癌(adenoid cystic carcinoma)

腺样基底细胞癌(adenoid basal carcinoma)

未分化癌(undifferentiated carcinoma)

神经内分泌肿瘤(neuroendocrine tumours) 

低级别神经内分泌肿瘤(low-grade neuroendocrine tumour)

类癌(carcinoid tumour)

非典型性类癌(atypical carcinoid tumour)

高级别神经内分泌癌(high-grade neuroendocrine carcinoma)

小细胞神经内分泌癌(small cell neuroendocrine carcinoma)

大细胞神经内分泌癌(large cell neuroendocrine carcinoma)


间叶性肿瘤和瘤样病变(mesenchymal tumours and tumour-like lesions)

良性(benign)

平滑肌瘤(leiomyoma)

横纹肌瘤(rhabdomyoma)

其他(others)

恶性(malignant)

平滑肌肉瘤(leiomyosarcoma)

横纹肌肉瘤(rhabdomyosarcoma)

腺泡状软组织肉瘤(alveolar soft-part sarcoma)

血管肉瘤(angiosarcoma)

恶性外周神经鞘瘤(malignant peripheral nerve sheath sarcoma)

其他肉瘤(other sarcomas)

脂肪肉瘤(liposarcoma)

未分化宫颈管肉瘤(undifferentiated endocervical sarcoma)

尤文肉瘤(Ewing sarcoma)

瘤样病变(tumour-like lesions)

手术后梭形细胞结节(postoperative spindle-cell nodule)

淋巴瘤样病变(lymphoma-like lesion)


上皮和间叶混合性肿瘤(mixed epithelial and mesenchymal tumours)

腺肌瘤(adenomyoma)

腺肉瘤(adenosarcoma)

癌肉瘤(carcinosarcoma)


黑色素细胞肿瘤(melanocytic tumours)

蓝痣(blue naevus)

恶性黑色素瘤(malignant melanoma)


生殖细胞型肿瘤(germ cell tumours)

卵黄囊瘤(yolk sac tumour)


淋巴组织和造血组织肿瘤(lymphoid and myeloid tumours)

恶性淋巴瘤(lymphomas)

髓系肿瘤(myeloid neoplasms)


继发性肿瘤(secondary tumours)


二.WHO子宫体肿瘤组织学分类(2014年版)

上皮性肿瘤及前期病变(epithelial tumours and precursors)

前期病变(precursors)

子宫内膜增生,不伴非典型性(hyperplasia without atypia)

子宫内膜非典型增生/子宫内膜上皮内瘤变( atypical hyperplasia / endometrioid intraepithelial neoplasia)

子宫内膜癌(endometrial carcinoma)

子宫内膜样癌(endometrioid carcinoma)

伴鳞状分化(squamous differentiation)

绒毛腺样(villoglandular)

分泌性(secretory)

黏液性癌(mucinous carcinoma)

浆液性上皮内癌(serous endometrial intraepithelial carcinoma)

浆液性癌(serous carcinoma)

透明细胞癌(clear cell carcinoma)

神经内分泌肿瘤 (neuroendocrine tumours) 

低级别神经内分泌肿瘤(low-grade neuroendocrine tumour)

类癌(carcinoid tumour)

高级别神经内分泌癌(high-grade neuroendocrine carcinoma)

小细胞神经内分泌癌(small cell neuroendocrine carcinoma)

大细胞神经内分泌癌(large cell neuroendocrine carcinoma)

混合细胞癌(mixed cell carcinoma)

未分化癌(undifferentiated carcinoma)

去分化癌(dedifferentiated carcinoma)

瘤样病变(tumour-like lesions)

息肉(polyp)

化生(metaplasia)

Arias-Stella反应(Arias-Stella reaction)

淋巴瘤样病变(lymphoma-like lesion)


间叶性肿瘤(mesenchymal tumours)

平滑肌瘤(leiomyoma)

富于细胞平滑肌瘤(cellular leiomyoma)

非典型性平滑肌瘤(leiomyoma with bizarre nuclei)

核分裂活跃的平滑肌瘤(mitotically active leiomyoma)

平滑肌瘤伴水肿变性(hydropic leiomyoma)

卒中性平滑肌瘤(apoplectic leiomyoma)

脂肪平滑肌瘤(lipomatous leiomyoma)

上皮样平滑肌瘤(epithelioid leiomyoma)

黏液样平滑肌瘤(myxoid leiomyoma)

绒毛叶样分隔性平滑肌瘤(Dissecting(cotyledonoid) leiomyoma)

弥漫性平滑肌瘤病(diffuse leiomyomatosis)

静脉内平滑肌瘤病(intravenous leiomyomatosis)

转移性平滑肌瘤(metastasizing leiomyoma)

恶性潜能未定的平滑肌肿瘤(smooth muscle tumour of uncertain malignant potential)

平滑肌肉瘤(leiomyosarcoma)

上皮样平滑肌肉瘤(epithelioid leiomyosarcoma)

黏液样平滑肌肉瘤(myxoid leiomyosarcoma)

子宫内膜间质和相关肿瘤(endometrial stromal and related tumours)

子宫内膜间质结节(endometrial stromal nodule)

低级别子宫内膜间质肉瘤 (low-grade endometrial stromal sarcoma)

高级别子宫内膜间质肉瘤 (high-grade endometrial stromal sarcoma)

未分化子宫内膜肉瘤(undifferentiated uterine sarcoma)

类似卵巢性索肿瘤的子宫肿瘤(uterine tumour resembling ovarian sex cord tumour)

杂类间叶性肿瘤(miscellaneous mesenchymal tumours)

横纹肌肉瘤(rhabdomyosarcoma)

血管周上皮样细胞肿瘤(perivascular epithelioid cell tumour)

良性(benign)

恶性(malignant)

其他(others)


混合性上皮和间叶肿瘤(mixed epithelial and mesenchymal tumours)

腺肌瘤(adenomyoma)

非典型息肉样腺肌瘤(atypical polypoid adenomyoma)

腺纤维瘤(adenofibroma)

腺肉瘤(adenosarcoma)

癌肉瘤(carcinosarcoma)


杂类肿瘤(miscellaneous tumours)

腺瘤样瘤(adenomatoid tumour)

神经外胚层肿瘤(neuroectodermal tumours)

生殖细胞肿瘤(germ cell tumours)


淋巴和造血肿瘤(lymphoid and myeloid tumours)

恶性淋巴瘤(lymphomas)

髓系肿瘤(myeloid neoplasms)


继发性性肿瘤(secondary tumours)