2019 WHO乳腺上皮源性肿瘤分类

 

Benign epithelial proliferations and precursors良性上皮增生和前驱病变

Usual ductal hyperplasia 普通型导管上皮增生

Columnar cell lesions, including flat epithelial atypia柱状细胞病变,包括扁平上皮非典型

Atypical ductal hyperplasia非典型导管增生

Adenosis and benign sclerosing lesions腺病和良性硬化性病变

Sclerosing adenosis硬化性腺病

8401/0   Apocrine adenoma大汗腺腺病

Microglandular adenosis微腺腺病

Radial scar / complex sclerosing lesion放射状瘢痕/复杂性硬化性病变

 

Adenomas腺瘤

8211/0   Tubular adenoma NOS小管腺瘤

8204/0   Lactating adenoma泌乳性腺瘤

8503/0   Duct adenoma NOS导管腺瘤非特指型

 

Epithelial-myoepithelial tumours 上皮肌上皮肿瘤

8940/0   Pleomorphic adenoma多形性腺瘤

8983/0   Adenomyoepithelioma NOS腺肌上皮瘤非特指型

8983/3   Adenomyoepithelioma with carcinoma腺肌上皮瘤伴癌

8562/3   Epithelial-myoepithelial carcinoma上皮肌上皮癌

 

Papillary neoplasms乳头状肿瘤

8503/0   Intraductal papilloma导管内乳头状瘤

8503/2   Ductal carcinoma in situ, papillary乳头状导管原位癌

8504/2   Encapsulated papillary carcinoma包裹性乳头状癌

8504/3   Encapsulated papillary carcinoma with invasion 包裹性乳头状癌伴浸润

8509/2   Solid papillary carcinoma in situ原位实性乳头状癌

8509/3   Solid papillary carcinoma with invasion实性乳头状癌伴浸润

8503/3   Intraductal papillary adenocarcinoma with invasion导管内乳头状腺癌伴浸润

 

Non-invasive lobular neoplasia非浸润性小叶性肿瘤

Atypical lobular hyperplasia 非典型小叶增生

8520/2   Lobular carcinoma in situ NOS小叶原位癌非特指型

Classic lobular carcinoma in situ经典型小叶原位癌

Florid lobular carcinoma in situ旺织性小叶原位癌

8519/2     Lobular carcinoma in situ, pleomorphic.多形性小叶原位癌

 

Ductal carcinoma in situ (DCIS)导管原位癌

8500/2   Intraductal carcinoma, non-infiltrating, NOS导管内癌,非浸润性,非特指

DCIS of low nuclear grade低级别核导管原位癌

DCIS of intermediate nuclear grade中级别核导管原位癌

DCIS of high nuclear grade高级别核导管原位癌

 

 

Invasive breast carcinoma浸润性乳腺癌

8500/3  Infiltrating duct carcinoma NOS 浸润性导管癌非特指型

8290/3  Oncocytic carcinoma嗜酸细胞癌

8314/3  Lipid-rich carcinoma富于脂质癌

8315/3  Glycogen-rich carcinoma 富于糖原癌

8410/3  Sebaceous carcinoma 皮脂腺癌

8520/3  Lobular carcinoma NOS 小叶癌非特指

8211/3  Tubular carcinoma小管癌

8201/3  Cribriform carcinoma NOS筛状癌非特指

8480/3  Mucinous adenocarcinoma黏液性癌

8470/3  Mucinous cystadenocarcinoma NOS黏液性囊性癌非特指

8507/3  Invasive micropapillary carcinoma of breast 浸润性微乳头状癌

8401/3  Apocrine adenocarcinoma大汗腺腺癌

8575/3  Metaplastic carcinoma NOS化生性癌非特指

 

Rare and salivary gland-type tumours少见和涎腺型癌

8550/3  Acinar cell carcinoma腺泡细胞癌

8200/3  Adenoid cystic carcinoma腺样囊性癌

Classic adenoid cystic carcinoma 经典型腺样囊性癌

Solid-basaloid adenoid cystic carcinoma 实性基地样腺样囊性癌

Adenoid cystic carcinoma with high-grade transformation

  腺样囊性癌伴高级别转化

3502/3     Secretory carcinoma分泌性癌

8430/3     Mucoepidermoid carcinoma粘液表皮样癌

8525/3     Polymorphous adenocarcinoma多形态腺癌

8509/3     Tall cell carcinoma with reversed polarity高细胞癌伴极向反转

 

Neuroendocrine neoplasms神经内分泌肿瘤

8240/3   Neuroendocrine tumour NOS神经内分泌肿瘤非特指

8240/3   Neuroendocrine tumour, grade 1 神经内分泌肿瘤1

8249/3   Neuroendocrine tumour, grade 2神经内分泌肿瘤2

8246/3   Neuroendocrine carcinoma NOS神经内分泌癌非特指

8041/3   Neuroendocrine carcinoma, small cell 小细胞神经内分泌癌

8013/3   Neuroendocrine carcinoma, large cell大细胞神经内分泌癌