2012年版WHO乳腺肿瘤分类
2012年版WHO乳腺肿瘤分类
上皮性肿瘤EPITHELIAL TUMOURS
微浸润癌Microinvasive carcinoma
浸润性乳腺癌Invasive breast carcinoma
浸润性癌，非特殊类型 Invasive carcinoma of no specialtype(NST)
•多形性癌 Pleomorphic carcinoma
•伴破骨巨细胞的癌Carcinoma with osteoclast-like stromal giant cells
•伴绒癌特征的癌Carcinoma with choriocarcinomatous features
•伴黑色素特征的癌 Carcinoma with melanotic features
浸润性小叶癌Invasive lobular carcinoma
•经典型小叶癌Classic lobular carcinoma
•实性型小叶癌Solid lobular carcinoma
•腺泡型小叶癌Alveolar lobular carcinoma
•多形性小叶癌 Pleomorphic lobular carcinoma
•小管小叶癌 Tubulolobular carcinoma
•混合性小叶癌 Mixed lobular carcinoma
小管癌Tubular carcinoma
筛状癌 Cribriform carcinoma
黏液癌 Mucinous carcinoma
伴有髓样癌特征的癌 Carcinoma with medullary features
髓样癌 Medullary carcinoma
不典型髓样癌 Atypical medullary carcinoma
具有髓样癌特征的浸润性癌(非特殊类型)
Invasive carcinoma NST with medullary features
伴大汗腺分化的癌 Carcinoma with apocrine differentiation
具有印戒样细胞分化的癌 Carcinoma with signet-ring-cell differentiation
浸润性微乳头状癌 Invasive micropapillary carcinoma
化生性癌，非特殊类型 Metaplastic carcinoma of no special type
低级别腺鳞癌 Low-grade adenosquamous carcinoma
纤维瘤病样化生性癌Fibromatosis-like metaplastic carcinoma
鳞状细胞癌 Squamous cell carcinoma
梭形细胞癌 Spindle cell carcinoma
具有间叶分化的化生性癌 Metaplastic carcinoma with mesenchymal differentiation
软骨分化 Chondroid differentiation
骨分化 Osseous differentiation
其他类型间叶分化 Other type of mesenchymal differentiation
混合性化生性癌 Mixed metaplastic carcinoma
肌上皮癌 Myoepithelial carcinoma
少见类型Rare types
具有神经内分泌特征的癌Carcinoma with neuroendocrine features
神经内分泌肿瘤，分化良好Neuroendocrine tumour ,well-differentiated
神经内分泌癌，低分化 （小细胞癌）
Neuroendocrine carcinoma,poorly differentiated (small cell carcinoma)
伴神经内分泌分化的癌 Carcinoma with neuroendocrine differentiated
分泌型癌 Secretory carcinoma
浸润性乳头状癌 Invasive papillary carcinoma
腺泡细胞癌 Acinic cell carcinoma
黏液表皮样癌 Mucoepidermoid carcinoma
多样性癌（类似涎腺多形性低度恶性腺癌） Plomorphous carcinoma
嗜酸细胞癌 Oncocytic carcinoma
富脂质癌 Lipid-rich carcinoma
富含糖原透明细胞癌 Glycogen-rich clear cell carcinoma
皮脂腺癌 Sebaceous carcinoma
涎腺/皮肤附件型肿瘤Salivary gland/skin adnexal type tumours
圆柱瘤 Cylindroma
透明细胞汗腺瘤 Clear cell hidradenoma
上皮-肌上皮肿瘤 Epithelial-myoepithelial tumours
多形性腺瘤 Pleomorphic adenoma
腺肌上皮瘤 Adenomyoepithelioma
腺肌上皮瘤癌变Adenomyoepithelioma with carcinoma
腺样囊性癌 Adenoid cystic carcinoma
前驱病变Precursor lesions
导管原位癌Ductal carcinoma in situ
小叶肿瘤 Lobular neoplasia
小叶原位癌 Lobular carcinoma in situ
经典型小叶原位癌Classic lobular carcinoma in situ
多形性小叶原位癌 Pleomorphic lobular carcinoma in situ
非典型小叶增生Atypical lobular heperplasia
导管增生性病变Intraductal proliferative lesions
普通型导管增生 Usual ductal hyperplasia
柱状上皮病变，包括平坦型不典型增生
Columnar cell lesions including flat epithelial atypia
非典型导管上皮增生 Atypical ductal hyperplasia
乳头状病变Papillary lesions
导管内乳头状瘤 Intraductal papilloma
伴异型增生的导管内乳头状瘤 Intraductal papilloma with atypical hyperplasia
伴导管内原位癌的导管内乳头状瘤 Intraductal papilloma with ductal caicinoma in situ
伴小叶原位癌的导管内乳头状瘤 Intraductal papilloma with lobular carcinoma in situ
导管内乳头状癌Intraductal papillary carcinoma
包裹性乳头状癌 Encapsulated papillary carcinoma
•伴有浸润的包裹性乳头状癌 Encapsulated papillary carcinoma with invasion
实性乳头状癌 Solid papillary carcinoma
•原位In situ
•浸润 Invasive
良性上皮增生Benign epithelial proliferations
硬化性腺病 Sclerosing adenosis
大汗腺腺病 Apocrine adenosis
微腺腺病 Microglandular adenosis
放射状瘢痕/复杂性硬化性病变 Radial scar/complex sclerosing lesion
腺瘤Adenomas
•管状腺瘤Tubular adenoma
•泌乳腺瘤 Lactating adenoma
•大汗腺腺瘤 Apocrine adenoma
•导管腺瘤 Ductal adenoma
间叶性肿瘤MESENCHYMAL TUMOURS
结节性筋膜炎Nodular fascietis
肌纤维母细胞瘤Myofibroblastoma
韧带样纤维瘤病Desmoid-type fibromatosis
炎性肌纤维母细胞肿瘤Inflacmatory myofibroblastic tumour
良性血管病变Benign vascular lesions
•血管瘤Haemangioma
•血管瘤病Angiomatosis
•非典型性血管病变Atypical vascular lesions
假血管瘤样增生Pseudoangiomatous stromal hyperplasia
颗粒细胞瘤Granular cell tumour
良性外周神经鞘瘤benign peripheral nerve-sheath tumours
•神经纤维瘤Neurofibroma
•施万细胞瘤Schwannoma
脂肪瘤Lipoma
•血管脂肪瘤Angiolipoma
脂肪肉瘤Liposarcoma
血管肉瘤Angiosarcoma
横纹肌肉瘤Rhabdomyosarcoma
骨肉瘤Osteosarcoma
平滑肌瘤Leiomyoma
平滑肌肉瘤Leiomyosarcoma
纤维上皮性肿瘤FIBROEPITHELIAL TUMOURS
纤维腺瘤Fibroadenoma
叶状肿瘤Phyllodes tumour
•良性Benign
•交界性Borderline
•恶性Malignant
•导管周间质肉瘤，低级别Periductal stromal tumour,low grade
错构瘤Hamartoma
乳头肿瘤TUMOURS OF THE NIPPLE
乳头腺瘤Nipple adenoma
汗管瘤样腺瘤Syringomatous tumour
乳头派杰氏病Paget disease of the nipple
恶性淋巴瘤MALIGNANT LYMPHOMA
弥漫性大B细胞淋巴瘤Diffuse large B-cell lymphoma
伯基特淋巴瘤Burkitt lymphoma
T细胞淋巴瘤T-cell lymphoma
ALK阴性的间变性大细胞淋巴瘤Anaplastic large cell lymphoma,ALK-negative
结外边缘区黏膜相关B细胞淋巴瘤Extranodal marginal-zone B-cell lymphoma
滤泡性淋巴瘤Follicular lymphoma
转移性肿瘤METASTATIC TUMOURS
男性乳腺肿瘤TUMOURS OF THE MALE BREAST
男性乳腺发育Gynaecomastia
癌Carcinoma
•浸润癌Invasive carcinoma
•原位癌In situ carcinoma
临床类型CLINICAL PATTERNS
炎性乳癌Inflacmatory carcinoma
双乳癌Bliateral breast carcinoma
