2016年WHO 中枢神经系统肿瘤分类
2016 WHO classification of tumours of the central nervous system
2016年WHO 中枢神经系统肿瘤分类
Diffuse astrocytic and oligodendroglial tumours
弥漫性星形和少突胶质细胞肿瘤
Diffuse astrocytoma, ID-mutant
弥漫性星形细胞瘤，IDH—突变型
Gemistocytic astrocytoma, IDH-mutant
肥胖型星形细胞瘤，IDH—突变型
Diffuse astrocytoma, IDH-wildtype
弥漫性星形细胞瘤，IDH—野生型
Diffuse astrocytoma, NOS
弥漫性星形细胞瘤，未明确
Anaplastic astrocytoma, IDH-mutant
间变型星形细胞瘤，IDH—突变型
Anaplastic astrocytoma, IDH-wildtype
间变型星形细胞瘤，IDH—野生型
Anaplastic astrocytoma, NOS
间变型星形细胞瘤，非特指型
Glioblastoma, IDH-wildtype
胶质母细胞瘤，IDH—野生型
Giant cell glioblastoma
巨细胞胶质母细胞瘤
Gliosarcoma
胶质肉瘤
Epithelioid glioblastoma
上皮样胶质母细胞瘤
Glioblastoma, IDH-mutant
胶质母细胞瘤，IDH—突变型
Glioblastoma, NOS
胶质母细胞瘤，非特指型
Diffuse midline glioma, H3 K27M-mutant
弥漫性中线胶质瘤，H3 K27M突变
Oligodendroglioma, IDH-mutant and 1p/19q-codeleted
少突胶质细胞瘤，IDH突变和1p/19q联合性缺失
Oligodendroglioma, NOS
少突胶质细胞瘤，非特指型
Anaplastic oligodendroglioma, IDH-mutant and 1p/19q-codeleted
间变型少突胶质细胞瘤，IDH突变和1p/19q联合性缺失
Anaplastic oligodendroglioma, NOS
间变型少突胶质细胞瘤，非特指型
Oligoastrocytoma, NOS
少突星形细胞瘤，非特指型
Anaplastic oligoastrocytoma, NOS
间变型少突星形细胞瘤，非特指型
Other astrocytic tumours
其他星形细胞肿瘤
Pilocytic astrocytoma
毛细胞星形细胞瘤
Pilomyxoid astrocytoma
毛细胞黏液样星形细胞瘤
Subependymal giant cell astrocytoma
室管膜下巨细胞星形细胞瘤
Pleomorphic xanthoastrocytoma
多形性黄色瘤样星形细胞瘤
Anaplastic pleomorphic xanthoastrocytoma
间变型多形性黄色星形细胞瘤
Ependymal tumours
室管膜肿瘤
Subependymoma
室管膜下瘤
Myxopapillary ependymoma
黏液乳头型室管膜瘤
Ependymoma
室管膜瘤
Papillary ependymoma
乳头型室管膜瘤
Clear cell ependymoma
透明细胞型室管膜瘤
Tanycytic ependymoma
伸长细胞型室管膜瘤
Ependymoma, RELA fusion-positive
室管膜瘤，RELA融合阳性
Anaplastic ependymoma
间变型室管膜瘤
Other gliomas
其他胶质瘤
Chordoid glioma of the third ventricle
第三脑室脊索样胶质瘤
Angiocentric glioma
血管中心性胶质瘤
Astroblastoma
星形母细胞瘤
Choroid plexus tumours
脉络丛肿瘤
Choroid plexus papilloma
脉络丛乳头状瘤
Atypical choroid plexus papilloma
非典型脉络丛乳头状瘤
Choroid plexus carcinoma
脉络丛癌
Neuronal and mixed neuronal-glial tumours
神经元和混合性神经元—胶质肿瘤
Dysembryoplastic neuroepithelial tumour
胚胎发育不良性神经上皮肿瘤
Gangliocytoma
节细胞瘤
Ganglioglioma
节细胞胶质瘤
Anaplastic ganglioglioma
间变性节细胞胶质瘤
Dysplastic cerebellar gangliocytoma
(Lhermitte-Duclos disease)
小脑发育不良性节细胞瘤（Lhermitte-Duclos病）
Desmoplastic infantile astrocytoma and Ganglioglioma
婴儿促纤维增生型星形细胞瘤/节细胞胶质瘤
Papillary glioneuronal tumour
乳头状胶质神经元肿瘤
Rosette-forming glioneuronal tumour
伴菊形团形成的胶质神经元肿瘤
Diffuse leptomeningeal glioneuronal tumour
弥漫性软脑膜胶质神经元肿瘤
Central neurocytoma
中枢神经细胞瘤
Extraventricular neurocytoma
脑室外神经细胞瘤
Cerebellar liponeurocytoma
小脑脂肪神经细胞瘤
Paraganglioma
副神经节瘤
Tumours of the pineal region
松果体区肿瘤
Pineocytoma
松果体细胞瘤
Pineal parenchymal tumour of intermediate differentiation
中分化松果体实质肿瘤
Pineoblastoma
松果体母细胞瘤
Papillary tumour of the pineal region
松果体区乳头状肿瘤
Embryonal tumours
胚胎性肿瘤
Medulloblastomas, Genetically defined
髓母细胞瘤，基因学分类
Medulloblastoma, WNT-activated
髓母细胞瘤，WNT活化
Medulloblastoma, SHH-activated and TP53-mutant
髓母细胞瘤，SHH活化和TP53突变型
Medulloblastoma, SHH-activated and TP53-wildtype
髓母细胞瘤，SHH活化和TP53野生型
Medulloblastoma, non-WNT/non-SHH
髓母细胞瘤，非WNT/非SHH
Medulloblastoma, group 3
髓母细胞瘤，3组
Medulloblastoma, group 4
髓母细胞瘤，4组
Medulloblastomas, histologically defined
髓母细胞瘤，组织学分类
Medulloblastoma, classic
髓母细胞瘤，经典型
Medulloblastoma, desmoplastic/nodular
髓母细胞瘤，促纤维增生/结节
Medulloblastoma with extensive nodularity
髓母细胞瘤伴广泛结节形成
Medulloblastoma, large cell / anaplastic
髓母细胞瘤，大细胞/间变型
Medulloblastoma, NOS
髓母细胞瘤，非特指型
Embryonal tumour with multilayered rosettes, C19MC-altered
胚胎性肿瘤伴多层菊形团，C19MC改变
Embryonal tumour with multilayered rosettes, NOS
胚胎性肿瘤伴多层菊形团，非特指型
Medulloepithelioma
髓上皮瘤
CNS neuroblastoma
中枢神经系统神经母细胞瘤
CNS ganglioneuroblastoma
中枢神经系统节细胞神经母细胞瘤
CNS embryonal tumour, NOS
中枢神经系统胚胎性肿瘤，非特指型
Atypical teratoid / rhabdoid tumour
非典型胚胎样/横纹肌样肿瘤
CNS embryonal tumour with rhabdoid features
中枢神经系统胚胎性肿瘤伴有横纹肌样特征
Tumours of the cranial and paraspinal nerves
颅神经和椎旁神经肿瘤
Schwannoma
神经鞘瘤
Cellular schwannoma
细胞性神经鞘瘤
Plexiform schwannoma
丛状神经鞘瘤
Melanotic schwannoma
黑色素性神经鞘瘤
Neurofibroma
神经纤维瘤
Atypical neurofibroma
非典型神经纤维瘤
Plexiform neurofibroma
丛状神经纤维瘤
Perineurioma
神经束膜瘤
Hybrid nerve sheath tumours
混合性神经鞘肿瘤
Malidnant peripheral nerve sheath tumour
恶性外周神经鞘瘤（MPNST）
Epithelioid MPNST
上皮型恶性外周神经鞘瘤
MPNST with perinurial differentiation
恶性外周神经鞘瘤伴神经束膜分化
Meningiomas
脑膜瘤
Meningioma
脑膜瘤
Meningothelial meningioma
脑膜上皮型脑膜瘤
Fibrous meningioma
纤维型脑膜瘤
Transitional meningioma
过渡型脑膜瘤
Psammomatous meningioma
砂粒体型脑膜瘤
Angiomatous meningioma
血管瘤型脑膜瘤
Microcystic meningioma
微囊型脑膜瘤
Secretory meningioma
分泌型脑膜瘤
Lymphoplasmacyte-rich meningioma
富于淋巴浆细胞型脑膜瘤
Metaplastic meningioma
化生型脑膜瘤
Chordoid meningioma
脊索样型脑膜瘤
Clear cell meningioma
透明细胞型脑膜瘤
Atypical meningioma
非典型脑膜瘤
Papillary meningioma
乳头型脑膜瘤
Rhabdoid meningioma
横纹肌样型脑膜瘤
Anaplastic (malignant) meningioma
间变型（恶性）脑膜瘤
Mesenchymal, non-meningothelial tumours
间叶性肿瘤，非脑膜上皮细胞来源肿瘤
Solitary fibrous tumour / haemangiopericytoma**
孤立性纤维性肿瘤/血管外周细胞瘤
Grade 1
1级
Grade 2
2级
Grade 3
3级
Haemangioblastoma
血管母细胞瘤
Haemangioma
血管瘤
Epithelioid haemangioendothelioma
上皮样血管内皮细胞瘤
Angiosarcoma
血管肉瘤
Kapposi sarooma
卡波西肉瘤
Ewing sarcoma / PNET
尤文肉瘤/PNET
Lipoma
脂肪瘤
Angiollpoma
血管脂肪瘤
Hibernoma
冬眠瘤
Liposarcoma
脂肪肉瘤
Dermoid-type fibromatosis
韧带样型纤维瘤病
Myofibroblastoma
肌纤维母细胞瘤
Inflammatory myofibroblastic tumour
炎性肌纤维母细胞瘤
Benign fibrous histiocytoma
良性纤维组织细胞瘤
Fibrosarcoma
纤维肉瘤
Undifferentiated pleomorphic sarcoma / Manignant fibrous histiocytoma
未分化多形性肉瘤/恶性纤维组织细胞瘤
Leiomyoma
平滑肌瘤
Leiomyosarcoma
平滑肌肉瘤
Rhabdomyoma
横纹肌瘤
Rhabdomyosarcoma
横纹肌肉瘤
Chondroma
软骨瘤
Chondrosarcoma
软骨肉瘤
Osteoma
骨瘤
Osteochondroma
骨软骨瘤
Osteosarcoma
骨肉瘤
Melanocytic tumours
黑色素细胞肿瘤
Meningeal melanocytosis
脑膜黑色素细胞增多症
Meningeal melanocytoma
脑膜黑色素细胞瘤
Meningeal melanoma
脑膜黑色素细胞瘤
Meningeal melanomatosis
脑膜黑色素瘤病
Lymphomas
淋巴瘤
Diffuse large B-cell lymphoma of the CNS
中枢神经系统弥漫性大B细胞淋巴瘤
Immunodeficiency-associated CNS lymphomas
免疫缺陷相关中枢神经系统淋巴瘤
AIDS-related diffuse large B-cell lymphoma
AIDS相关性弥漫性大B细胞淋巴瘤
EBV-positive diffuse large B-cell lymphoma. NOS
EBV阳性弥漫性大B细胞淋巴瘤，非特指型
Lymphomatoid granulomatosis
淋巴瘤样肉芽肿
Intravascular large B-cell lymphoma
血管内大B细胞淋巴瘤
Low-grade B-cell lymphomas of the CNS
中枢神经系统低级别B细胞淋巴瘤
T-cell and NK / T-cell lymphomas of the CNS
中枢神经系统T/NK细胞淋巴瘤
Anaplastic large cell lymphoma, ALK-positive
间变性大细胞淋巴瘤，ALK阳性
Anaplastic large cell lymphoma, ALK-negative
间变性大细胞淋巴瘤，ALK阴性
MALT lymphoma of the dura
硬脑膜黏膜相关淋巴组织边缘区淋巴瘤
Histiocytic tumours
组织细胞肿瘤
Langerhans cell histiocytosis
朗格汉斯细胞组织细胞增生
Erdheim-Chester disease
Erdheim-Chester病
Rosai-Dorfman disease
Rosai-Dorfman病
Juvenile xanthogranuloma
幼年黄色肉芽肿
Histiocytic sarcoma
组织细胞肉瘤
Germ cell tumours
生殖细胞肿瘤
Germinoma
生殖细胞瘤
Embryonal carcinoma
胚胎癌
Yolk sac tumour
卵黄囊瘤
Choriocarcinoma
绒毛膜癌
Teratoma
畸胎瘤
Mature teratoma
成熟性畸胎瘤
Immature teratoma
未成熟性畸胎瘤
Teratoma with malignant transformation
畸胎瘤伴恶性转化
Mixed germ cell tumour
混合性生殖细胞肿瘤
Tumours of the sellar region
鞍区肿瘤
Craniopharyngioma
颅咽管瘤
Adamantinomatous craniopharyngioma
造釉细胞型颅咽管瘤
Papillary craniopharyngioma
乳头状颅咽管瘤
Granular cell tumour of the sellar region
鞍区颗粒细胞瘤
Pituicytoma
垂体细胞瘤
Spindle cell oncocytoma
梭形细胞嗜酸细胞瘤
Metastatic tumours
转移性肿瘤
