2022年第五版WHO B 细胞肿瘤分类
以B细胞为主的肿瘤样病变Tumour-like lesions with B-cell predominance
类似于淋巴瘤的反应性富于B细胞的淋巴组织增生性病变
Reactive B-cell-rich lymphoid proliferations that can mimic lympboma
IgG4相关疾病IgG4-related disease
单中心巨大淋巴结增生症Unicentric Castleman disease
特发性多中心巨大淋巴结增生症 Idiopathic multicentric Castleman disease
KSHV/HHV8相关巨大淋巴结增生症KSHV/HHV8-associated multicentric Castleman disease
前驱B细胞肿瘤Precursor B-cell neoplasms
B 淋巴母细胞白血病/淋巴瘤B lymphoblastic leukemia/lymphoma
B 淋巴母细胞白血病/淋巴瘤，非特指型 (B-ALL/LBL，NOS)
B lymphoblastic leukemia/lymphoma，not otherwise specified (NOS)
B淋巴母细胞白血病/淋巴瘤伴高超二倍体
B lymphoblastic leukemia/lymphoma with high hyper-diploidy
B淋巴母细胞白血病/淋巴瘤伴亚二倍体
B lymphoblastic leukemia/lymphoma with hypo-diploidy
B 淋巴母细胞白血病/淋巴瘤伴iAMP21
B lymphoblastic leukemia/lymphoma with iAMP21
B淋巴母细胞白血病/淋巴瘤伴BCR::ABL1融合
B lymphoblastic leukemia/lymphoma with BCR::ABL1 fusion
B淋巴母细胞白血病/淋巴瘤伴BCR::ABL1样特征
B lymphoblastic leukemia/lymphoma with BCR-ABL1-like features
B淋巴母细胞白血病/淋巴瘤伴KMT2A 重排
B lymphoblastic leukemia/lymphoma with KMT2A rearranged
B淋巴母细胞白血病/淋巴瘤伴 ETV6::RUNX1融合
B lymphoblastic leukemia/lymphoma with ETV6::RUNX1 fusion
B淋巴母细胞白血病/淋巴瘤伴 ETV6::RUNX1样特征
B lymphoblastic leukemia/lymphoma with ETV6::RUNX1 like features
B淋巴母细胞白血病/淋巴瘤伴TCF3::PBX1融合
B lymphoblastic leukemia/lymphoma with TCF3::PBX1 fusion
B淋巴母细胞白血病/淋巴瘤伴 IL3-IGH融合
B lymphoblastic leukemia/lymphoma with IL3-IGH fusion
B淋巴母细胞白血病/淋巴瘤伴其他明确的基因异常
B-lymphoblastic leukaemia/lymphoma with other defined genetic abnormalities
成熟B细胞肿瘤 Mature B-Cell Neoplasms
瘤前和肿瘤性小淋巴细胞增生Pre-neoplastic and neoplastic small lymphocytic proliferations
单克隆B淋巴细胞增多症Monoclonal B-cell lymphocytosis
慢性淋巴细胞白血病/B小淋巴细胞淋巴瘤(CLL/SLL)
Chronic lymphocytic leukemia/small lymphocytic lymphoma
脾脏B细胞淋巴瘤/白血病Splenic B-cell lymphomas and leukaemias
毛细胞白血病(HCL) Hairy cell leukemia
脾边缘区淋巴瘤脾脏边缘区淋巴瘤(SMZL) Splenic B-cell marginal zone lymphoma
脾脏弥漫红髓小B细胞淋巴瘤Splenic diffuse red pulp small B-cell lymphoma
脾B细胞淋巴瘤/白血病伴显著核仁Splenic B-cell lymphoma/leukaemia with prominent nucleoli
淋巴浆细胞性淋巴瘤Lymphoplasmacytic lymphoma（LPL）
淋巴浆细胞性淋巴瘤Lymphoplasmacytic lymphoma（LPL）
边缘区淋巴瘤 marginal zone lymphoma（MZL）
结外黏膜相关淋巴组织边缘区淋巴瘤 (MALT淋巴瘤)
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
原发皮肤边缘区淋巴瘤
Primary cutaneous marginal zone lymphoma
淋巴结边缘区淋巴瘤Nodal marginal zone lymphoma（NMZL）
儿童边缘区淋巴瘤Paediatric marginal zone lymphoma
滤泡性淋巴瘤Follicular lymphoma
原位滤泡性肿瘤 In situ follicular neoplasia (ISFN)
滤泡性淋巴瘤Follicular lymphoma（FL）
十二指肠型滤泡性淋巴瘤Duodenal-type follicular lymphoma
儿童型滤泡型淋巴瘤Pediatric type follicular lymphoma
皮肤滤泡中心淋巴瘤Cutaneous follicle centre lymphoma
原发皮肤滤泡中心淋巴瘤Primary Cutaneous follicle centre lymphoma
套细胞淋巴瘤Mantle cell lymphoma(MCL)
原位套细胞肿瘤In situ mantle cell neoplasia (ISMCN)
套细胞淋巴瘤Mantle cell lymphoma
白血病性非淋巴结套细胞淋巴瘤Leukaemic non-nodal mantle cell lymphoma
惰性B细胞淋巴瘤的转化Transformations of indolent B-cell lymphomas
惰性B细胞淋巴瘤的转化Transformations of indolent B-cell lymphomas
大B细胞淋巴瘤large B-cell lymphoma
弥漫大B细胞淋巴瘤，非特指型 Diffuse large B-cell lymphoma (DLBCL), NOS
T细胞/组织细胞丰富型大B细胞淋巴瘤T cell/histiocyte-rich large B-cell lymphoma(THRLBCL)
弥漫性大B细胞淋巴瘤/高级别B细胞淋巴瘤伴MYC和BCL-2基因易位
Diffuse large B-cell lymphoma/High grade B-cell lymphomas (HGBL), with MYC and BCL2 translocations
ALK+ 大B细胞淋巴瘤ALK positive large B-cell lymphoma(ALK+ LBCL)
大B细胞淋巴瘤伴IRF4重排Large B-cell lymphoma with IRF4 rearrangement
高级别淋巴瘤伴11q异常High grade lymphoma with 11q aberration
淋巴瘤样肉芽肿病Lymphomatoid granulomatosis(LYG)
EBV阳性弥漫大B细胞淋巴瘤Epstein-Barr virus(EBV)-positive DLBCL
慢性炎症相关的弥漫大B细胞淋巴瘤DLBCL associated with chronic inflammation
纤维蛋白相关大B细胞淋巴瘤Fibrin-associated large B-cell lymphoma
积液相关大B细胞淋巴瘤Fluid overload-associated large B-cell lymphoma
浆母细胞性淋巴瘤Plasmablastic lymphoma（PBL）
原发性免疫豁免部位大B细胞淋巴瘤Primary large B-cell lymphoma of immune-privileged sites
原发性皮肤弥漫性大B细胞淋巴瘤，腿型Primary cutaneous DLBCL, leg type（PCLBCL, leg）
血管内大B细胞淋巴瘤Intravascular large B-cell lymphoma(IVLBCL)
原发性纵隔大B细胞淋巴瘤Primary mediastinal (thymic) large B-cell lymphoma（PMBL）
高级B细胞淋巴瘤，非特指High-grade B-cell lymphoma, NOS
Burkitt淋巴瘤 Burkitt lymphoma
Burkitt淋巴瘤 Burkitt lymphoma
KSHV/ hhv8相关B细胞淋巴增生和淋巴瘤
KSHV/HHV8-associated B-cell lymphoid proliferations and lymphomas
原发性渗出性淋巴瘤Primary effusion lymphoma
KSHV/ HHV8阳性弥漫大B细胞淋巴瘤KSHV/HHV8-positive diffuse large B-cell lymphoma
KSHV/ HHV8阳性生殖性淋巴增生性疾病KSHV/HHV8-positive germinotropic lymphoproliferative disorder
与免疫缺陷和调节失调相关的淋巴样增生和淋巴瘤
Lymphoid proliferations and lymphomas associated with immune deficiency and dysregulation
由免疫缺陷/失调引起的增生Hyperplasias arising in immune deficiency/dysregulation
免疫缺陷/调节失调引起的多形性淋巴增生性疾病
Polymorphic lymphoproliferative disorders arising in immune deficiency/dysregulation
EBV阳性黏膜皮肤溃疡EBV-positive mucocutaneous ulcer
免疫缺陷/调节失调引起的淋巴瘤Lymphomas arising in immune deficiency / dysregulation
先天性免疫缺陷淋巴增生和淋巴瘤
Inborn error of immunity-associated lymphoid proliferations and lymphomas
浆细胞肿瘤和其它具有副蛋白的疾病Plasma cell neoplasms and other diseases with paraproteins
单克隆γ病Monoclonal gammopathies
冷凝集素病Cold agglutinin disease重链病(HCD)
意义不明确的IgM单克隆γ病IgM monoclonal gammopathy of undetermined significance
意义不明确的非IGM单克隆γ病Non-lgM monoclonal gammopathy of undetermined significance
肾病表现单克隆γ病Monoclonal gammopathy of renal significance
具有单克隆免疫球蛋白沉积的疾病Diseases with monoclonal immunoglobulin deposition
免疫球蛋白相关淀粉样变Immunoglobulin-related (AL) amyloidosis
单克隆免疫球蛋白沉积病Monoclonal immunoglobulin deposition disease
重链病heavy chain disease
Mu重链病（Mu-HCD）Mu heavy chain disease
Gamma重链病（γ-HCD）Gamma heavy chain disease
Alpha重链病（α-HCD）Alpha heavy chain disease
浆细胞肿瘤 Plasma cell neoplasms
浆细胞瘤Plasmacytoma
浆细胞骨髓瘤Plasma cell myeloma
浆细胞肿瘤伴相关副肿瘤综合征
Plasma cell neoplasms with associated paraneoplastic syndrome
-POEMS 综合征
-TEMPI 综合征
- AESOP 综合征
霍奇金淋巴瘤 Hodgkin lymphoma (HL)
结节型淋巴细胞为主型霍奇金淋巴瘤 Nodular lymphocyte predominant Hodgkin lymphoma(NLPHL)
经典型霍奇金淋巴瘤 Classical Hodgkin lymphoma (CHL)
结节硬化型经典型霍奇金淋巴瘤Nodular sclerosis classical Hodgkin lymphoma( NSCHL)
混合细胞型经典型霍奇金淋巴瘤Mixed cellularity classical Hodgkin lymphoma（MCCHL）
淋巴细胞丰富型经典型霍奇金淋巴瘤Lymphocyte-rich classical Hodgkin lymphoma(LRCHL)
淋巴细胞消减型经典型霍奇金淋巴瘤Lymphocyte-depleted classical Hodgkin lymphoma(LDCHL)
