尿路上皮癌伴滋养叶分化
Urothelial Carcinoma With Trophoblastic Differentiation
赵明 程亮
更新时间：2020-10-27 15:45:00
概述：
发病部位：膀胱、输尿管、肾盂、尿道
诊断要点：
2.部分病例可出现绒毛膜癌样分化成分；
3.某些尿路上皮癌可出现血清β-HCG升高或免疫组化染色表达β-HCG但无形态学提示的滋养细胞分化证据，称为产β-HCG的尿路上皮癌。
免疫组织化学染色：
分子标记：
鉴别诊断：
预后：
治疗：
参考文献：
Shimada K, Nakamura M, Ishida E, et al. Urothelial carcinoma with plasmacytoid variants producing both human chorionic gonadotropin and carbohydrate antigen 19-9. Urology 2006;68:89l.e7-e10.
Dimhofer S, Koessler P, Ensinger C, et al. Production of trophoblastic hormones by transitional cell carcinoma of the bladder: association to tumor stage and grade. Hum Pathol1998;29:377-382.
Przybycin CG, McKenney JK, Nguyen JK, Shah RB, Umar SA, Harik L, Shih IM, Cox RM. Urothelial Carcinomas With Trophoblastic Differentiation, Including Choriocarcinoma: Clinicopathologic Series of 16 Cases. Am J Surg Pathol. 2020 Oct;44(10):1322-1330.
