目    录

髓系前体病变 Myeloid precursor lesions

引言 introduction

克隆性造血 Clonal Haematopoiesis

克隆性造血 Clonal Haematopoiesis

意义不明的克隆性细胞减少Clonal cytopenias of undetermined significanc

骨髓增殖性肿瘤  Myeloproliferative neoplasm（MPN）

慢性髓系白血病Chronic myeloid leukemia

慢性中性粒细胞白血病Chronic neutrophilic leukaemia（CNL）

慢性嗜酸粒细胞白血病Chronic eosinophilic leukaemia

真性红细胞增多症Polycythemia vera（PV）

原发性血小板增多症Essential thrombocythaemia（ET）

原发性骨髓纤维化Primary myelofibrosis(PMF)

幼年性粒单细胞白血病Juvenile myelomonocytic leukaemia

骨髓增生性肿瘤，非特指Myeloproliferative neoplasm,，NOS

肥大细胞增多症  Mastocytosis

皮肤肥大细胞增多症Cutaneous mastocytosis(CM)

系统性肥大细胞增多症Systemic mastocytosis(SM)

肥大细胞肉瘤Mast cell sarcoma (MCS)

骨髓增生异常肿瘤  Myelodysplastic neoplasms (MDS)

遗传学异常定义的骨髓增生异常肿瘤

Myelodysplastic neoplasms, with defining genetic abnormalities

骨髓增生异常肿瘤伴低原始细胞和5q缺失

Myelodysplastic neoplasm with low blasts and 5q deletion

骨髓增生异常肿瘤伴低原始细胞和SF3B1突变的

Myelodysplastic neoplasm with low blasts and SF3B1 mutation

骨髓增生异常肿瘤伴TP53双等位基因失活

Myelodysplastic neoplasm with biallelic TP53 nactivation

形态学定义的骨髓增生异常肿瘤Myelodysplastic neoplasms, morphologically defined

骨髓增生异常肿瘤伴低原始细胞Myelodysplastic neoplasm with low blasts

骨髓增生异常肿瘤伴，低增生Myelodysplastic neoplasm, hypoplastic

骨髓增生异常肿瘤伴原始细胞增多Myelodysplastic neoplasm with increased blasts

儿童骨髓增生异常肿瘤Myelodysplastic neoplasms of childhood

儿童骨髓增生异常肿瘤伴低原始细胞Childhood myelodysplastic neoplasm with low blasts

儿童骨髓增生异常肿瘤伴原始细胞增多

Childhood myelodysplastic neoplasm with increased blasts

骨髓增生异常/骨髓增殖性肿瘤  Myelodysplastic/myeloproliferative neoplasms (MDS/MPN)

慢性粒-单核细胞白血病Chronic myelomonocytic leukaemia (CMML)

骨髓增生异常/骨髓增殖性肿瘤伴中性粒细胞增多

Myelodysplastic/myeloproliferative neoplasm with neutrophilia

骨髓增生异常/骨髓增殖性肿瘤伴SF3B1突变寄血小板增多

Myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis

骨髓增生异常/骨髓增殖性肿瘤，非特指Myelodysplastic/myeloproliferative neoplasm, NOS

急性髓系白血病acute myeloid leukemia

基因异常定义的急性髓系白血病Acute myeloid leukaemia with defining genetic abnormalitie

急性早幼粒细胞白血病伴PML::RARA融合

Acute promyelocytic leukaemia with PML::RARA fusion

急性髓系白血病伴RUNX1::RUNX1T1融合

Acute myeloid leukaemia with RUNXI::RUNX1T1 fusion

急性髓系白血病伴CBFB::MYH11 融合

Acute myeloid leukaemia  with CBFB::MYHl1 fusion

急性髓系白血病伴DEK::NUP214融合

Acute myeloid leukaemia with DEK::NUP214 fusion

急性髓系白血病伴RBM15::MRTFA融合

Acute myeloid leukaemia with RBM15::MRTFA fusion

急性髓系白血病伴BCR::ABL1 融合

 Acute myeloid leukaemia with BCR-ABL1 fusion

急性髓系白血病伴KMT2A重排

Acute myeloid leukaemia with KMT2A rearrangement

急性髓系白血病伴MECOM重排

Acute myeloid leukaemia with MECOM  rearrangement

急性髓系白血病伴NUP98重排

Acute myeloid leukaemia with NUP98 rearrangement

急性髓系白血病伴NPM1突变

Acute myeloid leukaemia with mutated NPM1

急性髓系白血病伴CEBPA突变

Acute myeloid leukaemia with CEBPA mutation

急性髓系白血病，骨髓增生异常相关

Acute myeloid leukaemia, myelodysplasia-relate

急性髓系白血病伴其它特定基因改变

Acute myeloid leukaemia with other defined genetic alteration

急性髓系白血病伴骨髓增生异常相关改变  AML with myelodysplasia-related changes

由细胞分化定义的急性髓系白血病Acute myeloid leukaemia, defined by differentiation

急性髓系白血病伴微小分化Acute myeloid leukaemia with minimal differentiation

急性髓系白血病不伴成熟Acute myeloid leukaemia without maturation

急性髓系白血病伴成熟Acute myeloid leukaemia with maturation

急性粒-单核细胞白血病Acute myelomonocytic leukaemia

急性单核细胞白血病Acute monocytic leukaemia

急性红系白血病Acute erythroid leukaemia

急性原巨核细胞白血病Acute megakaryoblastic leukaemia

急性嗜碱性粒细胞白血病Acute basophilic leukaemia

髓系肉瘤  Myeloid sarcoma

髓系肿瘤，继发性Myeloid neoplasms, secondary

与前驱病变或遗传易感性相关的髓系肿瘤和增生

Myeloid neoplasms and proliferations associated with antecedent or predisposing conditions

细胞毒药物治疗后髓系肿瘤Myeloid neoplasm post cytotoxic therapy

遗传易感性相关的髓系肿瘤Myeloid neoplasms associated with germline predisposition

唐氏综合征相关的髓系增殖性疾病  Myeloid proliferations associated with Down syndrome

髓系或淋系肿瘤伴嗜酸性粒细胞增多及特定基因重排

Myloid lymphoid neoplasams with esonophilia and defined gene rearrangement

髓系/淋系肿瘤伴PDGFRA重排

Myeloid/lymphoid neoplasms with PDGFRA rearrangement

髓系/淋系肿瘤伴PDGFRB重排

Myeloid/lymphoid neoplasms with PDGFRB rearrangement

髓系/淋巴细胞系肿瘤伴FGFR1重排

Myeloid/lymphoid neoplasms with FGFR1 rearrangemen

髓系/淋系肿瘤伴JAK2重排Myeloid/lymphoid neoplasm with JAK2 rearrangement

髓系/淋系肿瘤伴FLT3重排Myeloid/lymphoid neoplasm with FLT3 rearrangement

髓系/淋系肿瘤伴ETV6::ABL1融合Myeloid/lymphoid neoplasm with ETV6::ABL1 fusion

髓系/淋系肿瘤伴其它酪氨酸激酶基因融合Myeloid/lymphoid neoplasms with other tyrosine kinase fusion genes